GBS
and CIDP are diseases of the peripheral nervous system in which the myelin
sheath (the insulation surrounding the nerves) becomes damaged. Without
the myelin sheath surrounding the nerve, messages going from our brain and
spinal cord cannot get to the muscles and other nerve receptors throughout our
body to tell them to work, causing weakness, loss of sensations and paralysis.
Demyelination at the paranodal
region (solid arrow). Arrow head points to the node of Ranvier.
Demyelination of a nerve
segment (solid arrow) between the two nodes of Ranvier (arrow heads).
This finding is frequently observed in the nerve biopsy of CIDP.
Department of
Neurology, Baylor College of Medicine
Most
types of peripheral neuropathy usually come on very slowly over several months
or years, such as the case of CIDP. On the other hand, if damage to the
nervous system comes on very rapidly, over the course of a few days, it fits
the category of GBS. We must remind you however that CIDP and GBS are
only two of the many different diseases that may occur to one's nervous system
and throughout the body.
The information on this site and the
links we provide is for general knowledge and support only. It is not to
be used as medical advice or in place of your physician. Please consult
your own doctor before making any changes or assumptions regarding medical care.
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